IL15 Overview
Molecule Name
Interleukin-15
Synonyms
Drug Development Progress
Drugs in Clinical Trials22
Approved Drugs0
Highest Development StagePhase 2 Clinical
Target Synonym
IL-15，Interleukin-15，IL15，Interleukin 15，MGC9721
Product Inquiry
Clinical Drug Information
| English Name | Research Code | Highest Development Stage | Company | Indication | Clinical Trial |
|---|---|---|---|---|---|
| EQ-101 | EQ101; EQ-101; BNZ132-1-40; BNZ-1; BNZ132-1; BNZ-01 | Phase 2 Clinical | Bioniz Therapeutics Inc | Alopecia; Alopecia Areata; Lymphoma, T-Cell, Cutaneous; Leukemia, Large Granular Lymphocytic | Details |
| Ordesekimab | HuMab-IL15; AMG-714; PRV-015 | Phase 2 Clinical | Provention Bio Inc, Genmab A/S, Amgen Inc | Arthritis, Rheumatoid; Celiac Disease; Psoriasis; Lymphoma, T-Cell; Vitiligo | Details |
| HCW-9218 | HCW-9218 | Phase 2 Clinical | HCW Biologics Inc | Solid tumours; Ovarian Neoplasms; Pancreatic Neoplasms; Pulmonary Fibrosis | Details |
| TEV-53408 | TEV-‘408; TEV-408; TEV-53408 | Phase 2 Clinical | Teva Pharmaceutical Industries Ltd | Gastrointestinal Diseases; Celiac Disease; Vitiligo | Details |
| HY-07121 | HY-07121; HY07121 | Phase 2 Clinical | Sichuan Huiyu Seacross Pharma Technology Ltd | Solid tumours | Details |
| NY-ESO-1 TCR/IL-15 NK | Phase 2 Clinical | The University Of Texas MD Anderson Cancer Center, Syena, Replay Holdings LLC | Sarcoma, Synovial; Multiple Myeloma; Liposarcoma, Myxoid | Details | |
| IL15-transpresenting WT1-targeted Dendritic Cell Vaccine(Antwerp University Hospital) | Phase 2 Clinical | Antwerp University Hospital | Liver Neoplasms; Ovarian Neoplasms; Esophageal Neoplasms; Pancreatic Neoplasms | Details | |
| CAR-5/IL-15-transduced CB-NK cell therapy | Phase 2 Clinical | The University Of Texas MD Anderson Cancer Center | Hematologic Neoplasms | Details | |
| Recombinant Human IL12/15-PDL1B Herpes Simplex Type I Oncolytic Virus (Cnbg-Virogin Biotech (Shanghai) Ltd) | VG-161 | Phase 2 Clinical | Cnbg-Virogin Biotech (Shanghai) Ltd | Solid tumours; Biliary Tract Neoplasms; Liver Neoplasms; Esophageal Neoplasms; Stomach Neoplasms; Neoplasms; Pancreatic Neoplasms; Cholangiocarcinoma; Sarcoma; Carcinoma, Hepatocellular | Details |
| Efbalropendekin alfa | XmAb-24306; RG-6323; RO-7310729; XmAb-306 | Phase 1 Clinical | Xencor Inc | Solid tumours; Multiple Myeloma | Details |
| SIM-0237 | SIM-0237; SIM-237 | Phase 1 Clinical | Simcere Pharmaceutical Group Ltd | Solid tumours; Urinary Bladder Neoplasms | Details |
| GTB-5550 | GTB-5550; B7H3 TriKE™; cam1615B7H3; GTB-5550 TriKE™ | Phase 1 Clinical | University Of Minnesota | Solid tumours | Details |
| CYTO-102 | CYTO-NK-102; CYTO-102; COH06 | Phase 1 Clinical | CytoImmune Therapeutics Inc | Lung Neoplasms; Carcinoma, Non-Small-Cell Lung | Details |
| VG-201 | VG-201 | Phase 1 Clinical | ViroGin Biotech Ltd | Solid tumours; Stomach Neoplasms; Esophageal Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung | Details |
| VG-203 | VG-203; VG2062; VG-2062 | Phase 1 Clinical | ViroGin Biotech Ltd, Shanghai Funuojian Biotechnology Co Ltd, Virogin Biotech (Shenzhen) Ltd, Fenojian Biotechnology (Nantong) Co Ltd | Solid tumours; Ovarian Neoplasms; Carcinoma, Renal Cell; Breast Neoplasms | Details |
| GIA-632 | GIA632; GIA-632 | Phase 1 Clinical | Novartis Ag | Immune System Diseases | Details |
| GTB-3650 | GTB-3650; GTB-360; OXS-3350; OXS-C3550 | Phase 1 Clinical | Masonic Cancer Center, University Of Minnesota | Bone Marrow Neoplasms; Myelodysplastic Syndromes; Leukemia, Myeloid, Acute | Details |
| BGB-R046 | BGBR046; BGB-R046 | Phase 1 Clinical | Beigene Guangzhou Biologics Manufacturing Co Ltd | Solid tumours; Neoplasm Metastasis | Details |
| RC-198 | RC-198 | Phase 1 Clinical | RemeGen Co Ltd | Solid tumours; Carcinoma, Renal Cell; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Transitional Cell; Colorectal Neoplasms; Melanoma; Carcinoma, Non-Small-Cell Lung | Details |
| ACTM-838 | ACTM-838; ACTM838 | Phase 1 Clinical | Actym Therapeutics Inc | Solid tumours | Details |
| QLF-32004 | QLF32004; QLF-32004 | Phase 1 Clinical | Qilu Pharmaceutical Co Ltd | Solid tumours; Neoplasms | Details |
| CALY-002 | CALY-002 | Phase 1 Clinical | Idd Biotech | Celiac Disease; Eosinophilic Esophagitis | Details |