Glycoprotein B (EBV)

Glycoprotein B (EBV) Overview

English NameEnvelope glycoprotein B, gBApproved Drugs0
Drugs in Clinical Trials2Target SynonymUL55
Highest Development StagePhase 2 Clinical
English NameEnvelope glycoprotein B, gB
Target SynonymUL55
Approved Drugs0
Drugs in Clinical Trials2
Highest Development StagePhase 2 Clinical

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Glycoprotein B (EBV) Background

Epstein-Bar Virus (EBV), also known as human herpesvirus 4, belongs to gamma herpes virus family and is a very common human virus worldwide. EBV causes infectious mononucleosis (IM) and also associates to some specific types of cancers such as Burkitt’s lymphoma (BL) and gastric carcinoma (GC). Glycoprotein B (gB) plays an important role in viral entry by binding with αvβ6/αvβ8 integrins to trigger the membrane fusion and entry process of epithelial cells, which makes it become an great target for EBV research.

Glycoprotein B (EBV) Synonyms

gB

Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
FiztasovimabNPC-21Phase 2 ClinicalNobelpharma Co LtdCytomegalovirus Infections
Details
TRL-345CMV-345; TRL-345Phase 1 ClinicalTrellis Bioscience LLCCytomegalovirus Infections
Details
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