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SLC39A6,LIV-1,ZIP6,Zinc transporter ZIP6,ZIP-6
Mouse LIV-1, His Tag (LV1-M5223) is expressed from human 293 cells (HEK293). It contains AA Leu 21 - Trp 335 (Accession # Q8C145-1).
Predicted N-terminus: Leu 21
Request for sequence
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 37.7 kDa. The protein migrates as 60-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Less than 1.0 EU per μg by the LAL method.
>90% as determined by SDS-PAGE.
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
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LIV-1 is also known as SLC39A6, ZIP-6 and Zinc transporter ZIP6. May act as a zinc-influx transporter. Highly expressed in the breast, prostate, placenta, kidney, pituitary and corpus callosum. Weakly expressed in heart and intestine. Also highly expressed in cells derived from an adenocarcinoma of the cervix and lung carcinoma. Up-regulated by estrogen in breast cancer cells lines.