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This product is in development. If you are interested in this product, please contact us directly. We will accelerate our R&D process according to your needs and reserve the product for you.
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FG4-H52H3-100ug
$400.00
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FG4-H52H3-1mg
$2,800.00
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FG4-H52H3
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  • Performance Data
  • Reviews & Citations
  • Important Statement
  • Resources

分子别名（Synonym）

FGF-4, Fibroblast growth factor 4, HST, HST-1

表达区间及表达系统（Source）

Human FGF-4, His Tag (FG4-H52H3) is expressed from human 293 cells (HEK293). It contains AA Ala 31 - Leu 206 (Accession # P08620-1).

Predicted N-terminus: Ala 31

蛋白结构（Molecular Characterization）

Online-Res(Ala 31 - Leu 206) P08620-1

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 21.2 kDa.

内毒素（Endotoxin）

制剂（Formulation）

Please contact us for detailed information.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. -20°C to -70°C for 12 months in lyophilized state;
  2. -70°C for 3 months under sterile conditions after reconstitution.

Background

Fibroblast growth factor-4 (FGF4) is expressed in embryonic stages and in adult tissues, where it plays critical roles in modulating multiple cellular functions. Fibroblast growth factor 4 (FGF4) is a multipotent growth factor and is highly expressed in various human cancers. In lung adenocarcinoma (ADC) cell lines, FGF4 could alter cell morphology, promote epithelial-mesenchymal transition-associated protein expression, and enhance cell proliferation, migration/invasion and colony initiation. In B-cell lymphoma, FGF4 secretion by cancer cells induces Jag1 expression in neighbor Endothelial cell that in turn activates Notch2 in lymphoma cells.