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Human SLC34A2 / NaPi2b Protein, Fc Tag (MALS verified)

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Cat. No. / Size
Price
Qty
SL2-H5253-100ug
$430.00
SL2-H5253-1mg
$2310.00
ETA of in-stock products:2 business days
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Product Details

  • Synonyms

    SLC34A2, NaPi2b, NaPi3b

  • Source

    Human SLC34A2 Protein, Fc Tag (SL2-H5253) is expressed from human 293 cells (HEK293). It contains AA Glu 249 - His 351 (Accession # O95436-2).

    Predicted N-terminus: Glu 249

    Request for sequence
  • Molecular Characterization

    SLC34A2 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a human IgG1 Fc tag at the C-terminus.

    The protein has a calculated MW of 38.2 kDa. The protein migrates as 55-65 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • Purity

    >95% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 24 months in lyophilized state;
    2. -70°C for 12 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • SDS-PAGE

    SLC34A2 SDS-PAGE

    Human SLC34A2 Protein, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    SLC34A2 SEC-MALS

    The purity of Human SLC34A2 Protein, Fc Tag (Cat. No. SL2-H5253) is more than 90% and the molecular weight of this protein is around 90-125 kDa verified by SEC-MALS.

    Report
  • Bioactivity-ELISA

     SLC34A2 ELISA

    Immobilized Human SLC34A2 Protein, Fc Tag (Cat. No. SL2-H5253) at 1 μg/mL (100 μL/well) can bind Upifitamab with a linear range of 0.06-4 ng/mL (QC tested).

    Protocol

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Background

SLC34A2 (Sodium-dependent phosphate transport protein 2B) is also known Solute carrier family 34 member 2, NaPi3b, NaPi-2b. Highly expressed in lung. Also detected in pancreas, kidney, small intestine, ovary, testis, prostate and mammary gland. In lung, it is found in alveolar type II cells but not in bronchiolar epithelium. May be involved in actively transporting phosphate into cells via Na+ cotransport. It may be the main phosphate transport protein in the intestinal brush border membrane. May have a role in the synthesis of surfactant in lungs' alveoli.

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  • Background