Mouse PTX3 / TSG-14 Protein, His Tag

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PT3-M52H6-100ug
$410.00
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PT3-M52H6-1mg
$3,170.00
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PT3-M52H6
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Synonyms

Pentraxin 3, TSG-14, TNFAIP5, Pentraxin-related protein PTX3, PTX3

Source

Mouse PTX3, His Tag (PT3-M52H6) is expressed from human 293 cells (HEK293). It contains AA Glu 18 - Ser 381 (Accession # P48759-1).

Predicted N-terminus: Glu 18

Molecular Characterization

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 41.9 kDa. The protein migrates as 45-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Endotoxin

Less than 1.0 EU per μg by the LAL method / rFC method.

Purity

>90% as determined by SDS-PAGE.

Formulation

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

Reconstitution

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

Shipping and Storage

This product is shipped at ambient temperature.

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • -20°C to -70°C for 12 months in lyophilized state;
  • -70°C for 3 months under sterile conditions after reconstitution.

Background

PTX3 is a prototypic long pentraxin consisting of a C-terminal 203-amino acid pentraxin-like domain coupled with an N-terminal 178-amino acid unrelated portion. Plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility. PTX3 can binds to C1q, but not C1s.