user
menu
letter
Sign InRegister
langEnglisharrow

Epstein-Barr virus Envelope Glycoprotein B (gB), His Tag (MALS verified)

Cat. No. / Size
Price
Availability
Qty
GLB-E52H3-100ug
$390.00
In Stock - Delivery in 1-2 business days
GLB-E52H3-1mg (500ug X 2)
$2,380.00
In Stock - Delivery in 1-2 business days
GLB-E52H3
Sub-Total :
$ 0
Customize Product Request Quote
Contact Us
Contact Us
Sub-Total:
$ 0
Request Quote
Product Details
Performance Data
Reviews & Citations
Resources
  • Product Details
  • Performance Data
  • Reviews & Citations
  • Important Statement
  • Resources
Synonyms

Glycoprotein B/gB (EBV)

Source

Epstein-Barr virus Envelope Glycoprotein B (gB), His Tag (GLB-E52H3) is expressed from human 293 cells (HEK293). It contains AA Gln 23 - Gly 685 (Accession # P03188 (W112H, Y113R, R428G, R429S, R430G, R431S, R432G, W193R, L194V, I195E, W196A)).

Predicted N-terminus: Gln 23

Molecular Characterization

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 76.0 kDa. The protein migrates as 90-100 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Endotoxin

Less than 1.0 EU per μg by the LAL method / rFC method.

Purity

>95% as determined by SDS-PAGE.

Formulation

Lyophilized from 0.22 μm filtered solution in PBS, 0.1 M Arginine, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

Reconstitution

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

Shipping and Storage

This product is shipped at ambient temperature.

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • -20°C to -70°C for 12 months in lyophilized state;
  • -70°C for 3 months under sterile conditions after reconstitution.
ACRO Quality Management System

Background

Epstein-Bar Virus (EBV), also known as human herpesvirus 4, belongs to gamma herpes virus family and is a very common human virus worldwide. EBV causes infectious mononucleosis (IM) and also associates to some specific types of cancers such as Burkitt’s lymphoma (BL) and gastric carcinoma (GC). Glycoprotein B (gB) plays an important role in viral entry by binding with αvβ6/αvβ8 integrins to trigger the membrane fusion and entry process of epithelial cells, which makes it become an great target for EBV research.