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Product Details
Synonyms
FOLR-1, FBP, FOLR, FRα
Source
Mouse FOLR1 Protein, Fc Tag (FO1-M5254) is expressed from human 293 cells (HEK293). It contains AA Thr 25 - Ser 232 (Accession # P35846-1).
Predicted N-terminus: Thr 25
Request for sequenceMolecular Characterization
Other Tags and Version Biotin & Other Labeled Version
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 50.7 kDa. The protein migrates as 57-65 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
Less than 1.0 EU per μg by the LAL method / rFC method.
Purity
>90% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.
Formulation
Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, pH7.5 with trehalose as protectant.
Contact us for customized product form or formulation.
Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Shipping and Storage
This product is shipped at ambient temperature.
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
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Performance Data
SDS-PAGE
Mouse FOLR1 Protein, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).
SEC-MALS
The purity of Mouse FOLR1 Protein, Fc Tag (Cat. No. FO1-M5254) is more than 90% and the molecular weight of this protein is around 100-125 kDa verified by SEC-MALS.
Report
Bioactivity-ELISA
Immobilized Folic acid -BSA at 5 μg/mL (100 μL/well) can bind Mouse FOLR1 Protein, Fc Tag (Cat. No. FO1-M5254) with a linear range of 0.1-1 ng/mL (QC tested).
Protocol
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Background
Recent Advances
Drug Development Progress- English Name：
Folate receptor alpha
- Category：
- Approved Drugs：
3 Details
- Drugs in Clinical Trials：
27 Details
- Highest Development Stage：
Approved
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