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Human Contactin-4 Protein, His Tag (MALS verified)

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Cat. No. / Size
Price
Qty
CO4-H52H3-100ug
$420.00
CO4-H52H3-1mg
$2940.00
ETA of in-stock products:2 business days
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Product Details

  • Synonyms

    Contactin-4

  • Source

    Human Contactin-4 Protein, His Tag (CO4-H52H3) is expressed from human 293 cells (HEK293). It contains AA Asp 19 - Ser 1000 (Accession # Q8IWV2-1).

    Predicted N-terminus: Asp 19

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  • Molecular Characterization

    Contactin-4 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 110.7 kDa. The protein migrates as 130-180 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • Purity

    >90% as determined by SDS-PAGE.

    >95% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • SDS-PAGE

    Contactin-4 SDS-PAGE

    Human Contactin-4 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    Contactin-4 SEC-MALS

    The purity of Human Contactin-4 Protein, His Tag (Cat. No. CO4-H52H3) is more than 95% and the molecular weight of this protein is around 115-155 kDa verified by SEC-MALS.

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Background

This gene encodes a member of the contactin family of immunoglobulins. Contactins are axon-associated cell adhesion molecules that function in neuronal network formation and plasticity. The encoded protein is a glycosylphosphatidylinositol-anchored neuronal membrane protein that may play a role in the formation of axon connections in the developing nervous system. Deletion or mutation of this gene may play a role in 3p deletion syndrome and autism spectrum disorders. Alternative splicing results in multiple transcript variants.

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