Select Language
IL-2 R beta & IL-2 R gamma
IL-2 R beta & IL-2 R gamma Overview
| English Name | Interleukin-2 receptor subunit gamma | Approved Drugs | 0 |
| Drugs in Clinical Trials | 14 | Target Synonym | Common Cytokine Receptor Gamma Chain，IL-2R Subunit Gamma，IL2RG，SCIDX，CD132，CIDX，IL-2RG，IMD4，Nonfunctional Common Cytokine Receptor Gamma Chain，Combined Immunodeficiency， X-Linked，Interleukin 2 Receptor Subunit Gamma，Interleukin-2 Receptor Subunit Gamma，Severe Combined Immunodeficiency，Cytokine Receptor Common Subunit Gamma，CD132 Antigen，GammaC，Interleukin 2 Receptor， Gamma，IL-2 Receptor Subunit Gamma，SCIDX1，P64 |
| Highest Development Stage | Phase 2 Clinical | ||
| English Name | Interleukin-2 receptor subunit gamma |
| Target Synonym | Common Cytokine Receptor Gamma Chain，IL-2R Subunit Gamma，IL2RG，SCIDX，CD132，CIDX，IL-2RG，IMD4，Nonfunctional Common Cytokine Receptor Gamma Chain，Combined Immunodeficiency， X-Linked，Interleukin 2 Receptor Subunit Gamma，Interleukin-2 Receptor Subunit Gamma，Severe Combined Immunodeficiency，Cytokine Receptor Common Subunit Gamma，CD132 Antigen，GammaC，Interleukin 2 Receptor， Gamma，IL-2 Receptor Subunit Gamma，SCIDX1，P64 |
| Approved Drugs | 0 |
| Drugs in Clinical Trials | 14 |
| Highest Development Stage | Phase 2 Clinical |
IL-2 R beta & IL-2 R gamma Product List
- Product Category
Protein (11)Cell (1)
- Product Status
Launched (12)
- Species
Human (4)Mouse (3)Rat (1)Rhesus macaque (2)Cynomolgus (2)
- Tag
Fc Tag (2)Fc Tag & Avi Tag (4)His Tag & Strep Tag (5)- (1)
- Conjugate
Unconjugated (7)Biotin-labeled (4)- (1)
Add to Cart
Total: 12
- 1
- 2
IL-2 R beta & IL-2 R gamma Background
Both Interleukin-2 receptor subunit beta and Interleukin-2 receptor subunit gamma are receptor for interleukin-2. Common subunit for the receptors for a variety of interleukins. Interacts with SHB upon interleukin stimulation. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.
IL-2 R beta & IL-2 R gamma Synonyms
IL-2 R beta & IL-2 R gamma,IL-2RB & IL-2RG
Clinical Drug Information
| English Name | Research Code | Highest Development Stage | Company | Indication | Clinical Trial |
|---|---|---|---|---|---|
| MB-107 | IND-14570; MB-107 | Phase 2 Clinical | National Heart, Lung And Blood Institute, National Institute Of Allergy And Infectious Diseases (Niaid), National Institute of Health, Islamabad, St. Jude Children'S Research Hospital | Immunologic Deficiency Syndromes; X-Linked Combined Immunodeficiency Diseases | Details |
| AWT-020 | AWT020; AWT-020; JS213; JS-213 | Phase 2 Clinical | Anwita Biosciences Inc | Autoimmune Diseases of the Nervous System; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Colorectal Neoplasms; Lung Neoplasms; Melanoma; Neoplasms; Solid tumours | Details |
| GI-101 | SIM-323; SIM323; SIM0323; GI-101 | Phase 2 Clinical | GI Innovation Inc | Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Neoplasms; Solid tumours; Uterine Cervical Neoplasms | Details |
| MB-501 | MB501; MB-501 | Phase 2 Clinical | Ascendis Pharma Inc | Neoplasms | Details |
| Pegenzileukin | IBI-127; THOR-707; SAR-444245 | Phase 2 Clinical | Synthorx Inc | Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Colorectal Neoplasms; Esophageal adenocarcinoma; Esophageal Squamous Cell Carcinoma; Head and Neck Neoplasms; Hodgkin Disease; Intestinal Neoplasms; Lymphoma, Large B-Cell, Diffuse; Melanoma; Mesothelioma; Multiple Myeloma; Neoplasm Metastasis; Oropharyngeal Neoplasms; Skin Neoplasms; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms | Details |
| LTC-004 | LTC004; LTC-004 | Phase 2 Clinical | Leto Laboratories Co Ltd | Colorectal Neoplasms; Neoplasms; Pancreatic Neoplasms; Sarcoma; Solid tumours | Details |
| TransCon IL-2 β/γ | Phase 2 Clinical | Ascendis Pharma A/S | Carcinoma, Non-Small-Cell Lung; Head and Neck Neoplasms; Ovarian Neoplasms; Solid tumours | Details | |
| TYF-IL-2Rg gene-modified autologous stem cells (Shenzhen Geno-Immune Medical Institute) | Phase 2 Clinical | Shenzhen Geno-Immune Medical Institute | X-Linked Combined Immunodeficiency Diseases | Details | |
| Simlukafusp alfa | FAP-IL2v; RG-7461; aFAP-IL2v; RO-6874281; FAP-IL2v FP | Phase 1 Clinical | F. Hoffmann-La Roche Ltd | Breast Neoplasms; Carcinoma, Renal Cell; Esophageal Neoplasms; Head and Neck Neoplasms; Melanoma; Solid tumours; Uterine Cervical Neoplasms | Details |
| BJ-001(Boji Biomedical Technology) | BJ-001 | Phase 1 Clinical | Boji Biomedical Technology (Hangzhou) Co Ltd | Communicable Diseases; Neoplasm Metastasis; Solid tumours | Details |
| ex vivo IL2RG stem cell-based gene therapy (Genethon/University College London/Hannover Medical School) | Phase 1 Clinical | Genethon | Severe Combined Immunodeficiency | Details | |
| PD 1-proIL-2v (Proviva Therapeutics) | PTX-912 | Phase 1 Clinical | Proviva Therapeutics Inc | Neoplasm Metastasis; Neoplasms; Solid tumours | Details |
| NL-201 (Neoleukin Therapeutics) | NL-201 | Phase 1 Clinical | Neoleukin Therapeutics Inc | Solid tumours | Details |
| Recombinant human interleukin 15(Beijing Kawin) | Phase 1 Clinical | Beijing Kawin Technology Share-Holding Co Ltd | Solid tumours | Details |
Product Reviews
E***e2021-09-06
2People LikeWe purchased this protein for BLI/SPR analysis. We got the fast and applicable support from Acrobiosystems for our SPR experiment.
- Overview
- Product List
- Product Reviews
- Clinical Drug Information
Share to: