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Your Position: Casa > Novel Anti-CAR Linker Antibodies

Anti-G4S Linker AntibodyAnti-Whitlow/218 Linker Antibody Coming soon!

Single B Cell Platform High Affinity Rabbit-derived Antibody High Specificity

Novel Anti-CAR Linker Antibodies

The development of CAR cell therapies requires precision and innovation at every step. ACROBiosystems delivers cutting-edge CAR linker antibodies, expertly designed to target G4S and Whitlow/218 linker sequences of scFv-based CARs. Labeled with fluorescent markers such as PE, APC, and Alexa Fluor™, these advanced tools set new standards in CAR-T characterization. Our premium-grade CAR linker antibodies, meticulously optimized for critical applications like cell activation and sorting, provide unparalleled solutions to drive excellence in CAR cell therapy research and development.

CAR Cell Characterization

CAR Cell Characterization

CAR Cell Activation

CAR Cell Activation

CAR Cell Sorting

CAR Cell Sorting

CAR Cell Enrichment

CAR Cell Enrichment

Product List

CAR Linker Cat. No. Species Product Description
G4S linker G4S-PFMY25 Rabbit PE-Labeled Monoclonal Anti-G4S linker Antibody, Rabbit IgG (016) (0.03% Proclin)
G4S linker G4S-AFMY25 Rabbit APC-Labeled Monoclonal Anti-G4S linker Antibody, Rabbit IgG (016) (0.03% Proclin)
G4S linker G4S-FAFYP1 Rabbit FITC-Labeled Monoclonal Anti-G4S linker Antibody, Rabbit IgG (016) (0.03% Proclin)
G4S linker G4S-AEFYP1 Rabbit Alexa Fluor™ 555-Labeled Monoclonal Anti-G4S linker Antibody, Rabbit IgG (016) (0.03% Proclin)
G4S linker G4S-ABFYP1 coming soon! Rabbit Alexa Fluor™ 647-Labeled Monoclonal Anti-G4S linker Antibody, Rabbit IgG (016) (0.03% Proclin)
G4S linker G4S-BLM25G0 Rabbit Biotinylated Monoclonal Anti-G4S linker Antibody, Rabbit IgG (016), premium grade
G4S linker G4S-CFM25G0 Rabbit PE-Labeled Monoclonal Anti-G4S linker Antibody, Rabbit IgG (016), premium grade
G4S linker G4S-HFM25G0 Rabbit APC-Labeled Monoclonal Anti-G4S linker Antibody, Rabbit IgG (016), premium grade

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High Affinity: Rabbit monoclonal antibody using proprietary single B cell antibody platform.

Exceptional Specificity: No non-specific binding to PBMCs.

Universal Species and Isotype Compatibility: Compatible with scFvs derived from any antibody isotype or species.

Versatile Applications: Effective in both in vivo and in vitro settings, regardless of antigen masking or serum.

Premium Grade: Ideal for CAR cell activation, sorting, and enrichment.

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Validation Data

Validated by flow cytometry, the PE-labeled Rabbit Anti-G4S Linker Antibody demonstrates high specificity in binding to CAR-like cells, including Anti-CD19 (G4S)4, Anti-MSLN (G4S)3, and Anti-CD22 (G4S)3.

Validated by flow cytometry
Validated by flow cytometry
Validated by flow cytometry

Flow cytometric analysis of Anti-CD19 CAR-293/Anti-MSLN CAR-293//Anti-CD2 CAR-293 cells staining with PE-Labeled Monoclonal Anti-G4S linker Antibody, Rabbit IgG (016) (Cat. No. G4S-PFMY25) at 1:50 dilution (2 μL of the antibody stock solution corresponds to labeling of 1e6 cells in a final volume of 100 µL), compared with isotype control antibody. PE signal was used to evaluate the binding activity.

Extremely low non-specific signal: validated by PBMC double staining

Validated by flow cytometry

Non-specificity of PE-Labeled Monoclonal Anti-G4S linker Antibody, Rabbit IgG (016), premium grade (Cat. No. G4S-CFM25G0) binding to CD3+ cells present in human PBMC. 5e5 of human PBMCs were simultaneously stained with FITC-labeled anti-CD3 antibody and PE-Labeled Anti-G4S linker Antibody (016) (2 μL of the antibody stock solution corresponds to labeling of 5e5 cells in a final volume of 100 µL) and washed and then analyzed with FACS. Both FITC and PE positive signals was used to evaluate the non-specific binding activity to human CD3+ cells (QC tested).

Superior positive Signal: outperforming competitors

Validated by flow cytometry

Flow cytometric analysis of Anti-CD19 CAR-293 cells staining with PE-Labeled Monoclonal Anti-G4S linker Antibodies (Cat. No. G4S-PFMY25). PE signal was used to evaluate the binding activity of anti-G4S linker antibody. The biological activity level of ACRO is superior to competitor C.

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